| Dietary intakes of nitrate, nitrite and NDMA in the Finnish Mobile Clinic Health Examination Survey. | |
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MedLine Citation:
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PMID: 8799716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Concern about potential health hazards of nitrate, nitrite and N-nitroso compounds necessitates calculations of exposures to these compounds and their distribution in normal populations. This study describes dietary intake of nitrate (NO3-), nitrite (NO2-) and N-nitrosodimethylamine (NDMA) among 5304 adult men and 4750 women, who participated in the Finnish Mobile Clinic Health Examination Survey in 1967-72. Food consumption data for each individual over the preceding year were collected by a dietary history interview. Intakes of nitrate, nitrite and NDMA from vegetables, fruits, cheese, meat and fish products were calculated using available values mainly derived from Finland and other countries in northern Europe. Nitrate and nitrite from drinking water were not included in the study. Mean daily dietary intake of nitrate was 77 mg, of nitrite 5.3 mg, and of NDMA 0.05 microgram respectively. Intake of NDMA from beer, estimated in a part of the study population, was 0.07 microgram per day. More than 90% of dietary nitrate was derived from vegetables, including potatoes. Nitrite was mainly provided by cured meat products. Cured meat products and smoked and salted fish were important food sources of NDMA. The total daily intake of nitrate was similar in men and women, whereas intakes of nitrite and NDMA were higher in men than in women. The diet of farmers was characterized by lower amounts of nitrate, nitrite and NDMA, whereas white collar workers and those employed in industry had higher intakes. Current smokers were exposed to higher dietary intakes of nitrate, nitrite and NDMA than non-smokers. Intakes of dietary nitrate, nitrite and NDMA estimated on an individual level are suggested to be useful in evaluating the health effects of these compounds in epidemiological studies. |
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Authors:
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J Dich; R Järvinen; P Knekt; P L Penttilä |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Food additives and contaminants Volume: 13 ISSN: 0265-203X ISO Abbreviation: Food Addit Contam Publication Date: 1996 Jul |
Date Detail:
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Created Date: 1997-02-24 Completed Date: 1997-02-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8500474 Medline TA: Food Addit Contam Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 541-52 Citation Subset: IM |
Affiliation:
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Department of Cancer Epidemiology, Radiumbemmet, Karolinska Hospital and Institute, Stockholm, Sweden. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Animals Cheese Diet* Dimethylnitrosamine / administration & dosage* Female Finland Fishes Fruit Health Surveys Humans Male Meat Products Middle Aged Nitrates / administration & dosage* Nitrites / administration & dosage* Vegetables |
| Chemical | |
Reg. No./Substance:
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0/Nitrates; 0/Nitrites; 62-75-9/Dimethylnitrosamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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