| Dietary intake of vitamin C and vitamin E and the development of hypertensive disorders of pregnancy. | |
| | |
MedLine Citation:
|
PMID: 15734087 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: To explore the relationship, if any, between dietary intake of the antioxidant vitamins C and E, and the development of pre-eclampsia and gestational hypertension. STUDY DESIGN: A prospective cohort study of pregnant women attending the antenatal clinic of the Women's and Children's Hospital in Adelaide, Australia, was carried out between April and July 2001. Women completed a semi-quantitative 116-item food frequency questionnaire (FFQ). Women's medical records were viewed after birth to collect data on pregnancy outcomes. Relationships were explored through cross-tabulations, chi-square analysis, and adjustments were made for potential confounders using binary logistic regression. RESULTS: A total of 299 women completed the FFQ. Median intake of vitamin C was 188 mg and for vitamin E was 6.74 mg. There was no relationship between the intake of vitamin C and hypertensive disorders of pregnancy. For vitamin E, being in the lowest quartile of intake, was associated with an increased risk of hypertensive disorders (RR 1.75, 95% CI 1.11-2.75, P = 0.02). This relationship was confirmed after adjusting for the confounding factors of maternal age and parity. CONCLUSIONS: Little support was found for a relationship between dietary intake of vitamin C and the development of hypertensive disorders of pregnancy. Low vitamin E intake was associated with a significant increase in the risk of hypertensive disorders of pregnancy, even after adjustments were made for confounding factors. Further research is required to investigate whether supplementation above dietary intake of antioxidant vitamins influences the risk of hypertensive disorders of pregnancy. |
| | |
Authors:
|
Alice R Rumbold; Frederike H E Maats; Caroline A Crowther |
Related Documents
:
|
15598727 - Association between childhood and adulthood socioeconomic position and pregnancy induce... 10877987 - Hypertension and factors associated with metabolic syndrome at follow-up at 15 years in... 19338987 - Hypertensive pregnancy complications in poor and normal responders after in vitro ferti... 23256267 - Recurrent seizures in pregnancy-epilepsy or eclampsia: a diagnostic dilemma? a case rep... 22585317 - Dna sequencing of maternal plasma to identify down syndrome and other trisomies in mult... 18302107 - Assisted reproductive technologies and pregnancy outcomes: mechanistic insights from an... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 119 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 2005 Mar |
Date Detail:
|
Created Date: 2005-02-28 Completed Date: 2005-07-15 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: Ireland |
Other Details:
|
Languages: eng Pagination: 67-71 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynaecology, Maternal and Perinatal Clinical Trials Unit, The University of Adelaide, South Australia, Australia. alice.rumbold@adelaide.edu.au |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Antioxidants* Ascorbic Acid* Diet* Diet Records Female Humans Hypertension, Pregnancy-Induced / etiology, physiopathology* Pregnancy Pregnancy Outcome Prospective Studies Vitamin E* |
| Chemical | |
Reg. No./Substance:
|
0/Antioxidants; 1406-18-4/Vitamin E; 50-81-7/Ascorbic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lipid peroxidation, antioxidant defense, status of trace metals and leptin levels in preeclampsia.
Next Document: Lipid peroxidation in the peritoneal fluid of infertile women with peritoneal endometriosis.