Document Detail


Dietary intake of vitamin B6 and concentration of vitamin B6 in blood samples of German vegans.
MedLine Citation:
PMID:  16925884     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The study aimed to evaluate the dietary vitamin B6 intake and determine the vitamin B6 concentration in blood samples of German vegans. DESIGN AND SETTING: Cross-sectional study with 33 examination sites all over Germany. Subjects Ninety-three vegans (50 females) with a mean (+/- standard deviation (SD)) age of 43.7 +/- 15.7 years who took no vitamin supplements. METHODS: Dietary intake was assed using a semi-quantitative food-frequency questionnaire. Erythrocyte aspartate aminotransferase activity coefficient (EAST-AC) was calculated as the ratio of stimulated (pyridoxal 5'-phosphate added) to unstimulated activity in blood samples that were provided after an overnight fast. RESULTS: Mean +/- SD vitamin B6 intake was 2.83 +/- 0.98 mg day(-1) and mean +/- SD protein intake was 56.6 +/- 21.7 g day(-1). Of the participants 4% showed vitamin B6 intakes lower than daily recommended intakes for Germany, 16% showed EAST-AC > 1.85, and a further 58% showed EAST-AC of 1.5-1-85. Moderate vegans were affected to a lesser extent than strict vegans. None of the established confounders was a significant predictor of EAST-AC. In logistic regression analyses the contribution of nutriments and cereals to pyridoxine intake was the only predictor of EAST-AC classified as < or = 1.85 and > 1.85, respectively. CONCLUSIONS: In spite of the high total intake of vitamin B6, an adequate concentration in blood samples could not be realised for a majority of the participants. Due to the health implications of a marginal pyridoxine status, vegans should be encouraged to include foods with a high bioavailability of pyridoxine, such as beans, lentils and bananas, in the daily diet.
Authors:
A Waldmann; B Dörr; J W Koschizke; C Leitzmann; A Hahn
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Public health nutrition     Volume:  9     ISSN:  1368-9800     ISO Abbreviation:  Public Health Nutr     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-23     Completed Date:  2007-01-09     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9808463     Medline TA:  Public Health Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  779-84     Citation Subset:  IM    
Affiliation:
Institute of Food Science, University of Hannover, Wunstorfer Strasse 14, D-30453 Hannover, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aspartate Aminotransferases / metabolism
Biological Availability
Cross-Sectional Studies
Diet, Vegetarian*
Erythrocytes / enzymology
Female
Germany
Humans
Logistic Models
Male
Nutrition Assessment*
Nutritional Status*
Questionnaires
Vitamin B 6 / administration & dosage*,  blood*
Vitamin B 6 Deficiency / blood,  epidemiology,  prevention & control
Vitamin B Complex / administration & dosage*,  blood
Chemical
Reg. No./Substance:
12001-76-2/Vitamin B Complex; 8059-24-3/Vitamin B 6; EC 2.6.1.1/Aspartate Aminotransferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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