Document Detail


Dietary intake of selected nutrients affects bacterial vaginosis in women.
MedLine Citation:
PMID:  17709453     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bacterial vaginosis (BV), a condition of altered vaginal flora, is associated with various adverse reproductive health outcomes. We evaluated the association between diet and the presence of BV in a subset of 1521 women (86% African-American) from a larger study of vaginal flora. Participants completed the Block Food Questionnaire and clinical assessments and self-report measures of sexual and hygiene behavior. A total of 42% of the women were classified as having BV (Nugent score > or = 7). Severe BV (Nugent score > or = 9 and vaginal pH > or = 5) was present in 14.9% of the women. BV was associated [adjusted OR (AOR)] with increased dietary fat (1.5, 1.1-2.4) after adjusting for other energy nutrients and behavioral and demographic covariates. Severe BV was associated with total fat (2.3, 1.3-4.3), saturated fat (2.1, 1.2-3.9), and monounsaturated fat (2.2, 1.2-4.1). Energy intake was only marginally associated (P = 0.05) with BV (1.4, 1.0-1.8). There were significant inverse associations between severe BV and intakes of folate (0.4, 0.2-0.8), vitamin E (0.4, 0.2-0.8), and calcium (0.4, 0.3-0.7). We conclude that increased dietary fat intake is associated with increased risk of BV and severe BV, whereas increased intake of folate, vitamin A, and calcium may decrease the risk of severe BV.
Authors:
Yasmin H Neggers; Tonja R Nansel; William W Andrews; Jane R Schwebke; Kai-fun Yu; Robert L Goldenberg; Mark A Klebanoff
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural    
Journal Detail:
Title:  The Journal of nutrition     Volume:  137     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-21     Completed Date:  2007-10-11     Revised Date:  2013-03-27    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2128-33     Citation Subset:  IM    
Affiliation:
Department of Human Nutrition, University of Alabama, Tuscaloosa, AL 35487, USA. yneggers@ches.ua.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Carbohydrates / pharmacology
Diet*
Female
Humans
Lipids / pharmacology
Middle Aged
Nutrition Surveys
Proteins / pharmacology
Vaginosis, Bacterial / epidemiology*,  microbiology
Grant Support
ID/Acronym/Agency:
N01-HD-8-3293/HD/NICHD NIH HHS; Z01 HD002535-09/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Carbohydrates; 0/Lipids; 0/Proteins
Comments/Corrections
Comment In:
J Nutr. 2007 Sep;137(9):1997-8   [PMID:  17709432 ]

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