Document Detail


Dietary hyperphagia and obesity: what causes them?
MedLine Citation:
PMID:  2657817     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diets that cause animals to overeat and become obese have been used in many investigations of obesity. Most of this research, however, has concentrated on the consequences rather than the causes of overeating. Furthermore, in most studies, several nutritional variables were manipulated simultaneously, making cause and effect relationship impossible to disentangle. Consequently, progress has been slow. Diets could alter energy intake by virtue of their effects on oral-sensory, gastrointestinal or postabsorptive effects. Palatability is the most popular oralsensory hypothesis but the empirical basis for this hypothesis is particularly weak. A substantial body of evidence is consistent with the possibility that the osmotic effects of diets in the gastrointestinal tract and metabolic postabsorptive factors may play a major role in dietary hyperphagia and obesity. Suggestions for future research directions are offered.
Authors:
I Ramirez; M G Tordoff; M I Friedman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Physiology & behavior     Volume:  45     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-07-07     Completed Date:  1989-07-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  163-8     Citation Subset:  IM    
Affiliation:
Monell Chemical Senses Center, Philadelphia, PA 19104.
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Weight*
Dietary Carbohydrates / metabolism
Dietary Fats / metabolism
Energy Metabolism
Feeding Behavior* / physiology
Rats
Taste* / physiology
Water-Electrolyte Balance
Grant Support
ID/Acronym/Agency:
AM34375/AM/NIADDK NIH HHS; DK35014/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Fats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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