| Dietary glycemic index and risk of type 2 diabetes mellitus in middle-aged Japanese men. | |
| | |
MedLine Citation:
|
PMID: 21803381 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
This cohort study investigated the association between dietary glycemic index (GI), glycemic load (GL), and the incidence of type 2 diabetes mellitus in middle-aged Japanese men, and the effect of insulin resistance and pancreatic B-cell function on the association. Participants were 1995 male employees of a metal products factory in Japan. Dietary GI and GL were assessed using a self-administered diet history questionnaire. The incidence of diabetes was detected in annual medical examinations over a 6-year period. The association between GI, GL, and the incidence of diabetes was evaluated using Cox proportional hazards models. During the study, 133 participants developed diabetes. Age- and body mass index-adjusted hazard ratios across the GI quintiles were 1.00 (reference), 1.62, 1.50, 1.68, and 1.80; and those of GL were 1.00 (reference), 1.07, 1.48, 0.95, and 0.98. The hazard ratio for the highest GI quintile was significantly greater than that for the lowest quintile. The influence of GI was more pronounced in the lowest insulin resistance subgroups. GI and pancreatic B-cell function were independently associated with the incidence of type 2 diabetes mellitus; participants with low B-cell function and the highest tertile of GI had the highest risk of diabetes. Dietary GI is associated with the incidence of diabetes in middle-aged Japanese men. GI and B-cell function were independently associated with incidence of diabetes. |
| | |
Authors:
|
Masaru Sakurai; Koshi Nakamura; Katsuyuki Miura; Toshinari Takamura; Katsushi Yoshita; Yuko Morikawa; Masao Ishizaki; Teruhiko Kido; Yuchi Naruse; Yasushi Suwazono; Shuichi Kaneko; Satoshi Sasaki; Hideaki Nakagawa |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-29 |
Journal Detail:
|
Title: Metabolism: clinical and experimental Volume: - ISSN: 1532-8600 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-8-1 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375267 Medline TA: Metabolism Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Epidemiology and Public Health, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Temporal and geographical trends in the genotoxic effects of marine sediments after accidental oil s...
Next Document: Passion fruit flowers: Kunitz trypsin inhibitors and cystatin differentially accumulate in developin...