Document Detail


Dietary fructooligosaccharides and potential benefits on health.
MedLine Citation:
PMID:  20119826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fructooligosaccharides (FOS) are oligosaccharides that occur naturally in plants such as onion, chicory, garlic, asparagus, banana, artichoke, among many others. They are composed of linear chains of fructose units, linked by beta (2-1) bonds. The number of fructose units ranges from 2 to 60 and often terminate in a glucose unit. Dietary FOS are not hydrolyzed by small intestinal glycosidases and reach the cecum structurally unchanged. There, they are metabolized by the intestinal microflora to form short-chain carboxylic acids, L -lactate, CO(2), hydrogen and other metabolites. FOS have a number of interesting properties, including a low sweetness intensity; they are also calorie free, non-cariogenic and are considered as soluble dietary fibre. Furthermore, FOS have important beneficial physiological effects such as low carcinogenicity, a prebiotic effect, improved mineral absorption and decreased levels of serum cholesterol, triacylglycerols and phospholipids. Currently FOS are increasingly included in food products and infant formulas due to their prebiotic effect stimulate the growth of nonpathogenic intestinal microflora. Their consumption increases fecal bolus and the frequency of depositions, while a dose of 4-15 g/day given to healthy subjects will reduce constipation, considered one of the growing problems of modern society, and newborns during the first months of life.
Authors:
M Sabater-Molina; E Larqu?; F Torrella; S Zamora
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of physiology and biochemistry     Volume:  65     ISSN:  1138-7548     ISO Abbreviation:  J. Physiol. Biochem.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812509     Medline TA:  J Physiol Biochem     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  315-28     Citation Subset:  IM    
Affiliation:
Department of Physiology, University of Murcia, Spain. mariasm@um.es
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MeSH Terms
Descriptor/Qualifier:
Blood Glucose / drug effects
Carbohydrate Sequence
Colonic Neoplasms / prevention & control
Constipation / drug therapy
Dietary Carbohydrates / pharmacology*
Fatty Acids, Volatile / metabolism
Humans
Immune System / drug effects
Infant
Infant Formula / chemistry
Infant, Newborn
Insulin / blood
Intestinal Absorption / drug effects
Lipid Metabolism / drug effects
Milk, Human
Minerals / metabolism
Oligosaccharides / pharmacology*,  therapeutic use*
Prebiotics*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Dietary Carbohydrates; 0/Fatty Acids, Volatile; 0/Idolax; 0/Minerals; 0/Oligosaccharides; 0/Prebiotics; 11061-68-0/Insulin

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