Document Detail

Dietary fats and blood pressure.
MedLine Citation:
PMID:  6596055     Owner:  NLM     Status:  MEDLINE    
The blood pressure lowering effect of elevating the dietary polyunsaturated/saturated (P/S) ratio has been assessed in a randomised, controlled trial in normotensive volunteers. Subjects were allocated either to a control group who ate a low P/S ratio diet throughout, or to one of two experimental groups who ate a high P/S ratio diet for one of two six week experimental periods. There were significant changes in estimated dietary P/S ratio and measured changes in plasma fatty acids and buccal mucosal cell phospholipids. Changes in blood pressure were not related to changes in P/S ratio. There were no changes in other factors which may have confounded the relationship between blood pressure and P/S ratio change. This study suggests that P/S ratio change, without changing other nutrients, does not affect blood pressure in normotensive subjects.
B M Margetts; L J Beilin; B K Armstrong; R Vandongen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  14     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1985-01-28     Completed Date:  1985-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  444-7     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / drug effects*
Dietary Fats / metabolism,  pharmacology*
Double-Blind Method
Fats, Unsaturated / metabolism,  pharmacology*
Linoleic Acid
Linoleic Acids / metabolism
Middle Aged
Random Allocation
Reg. No./Substance:
0/Dietary Fats; 0/Fats, Unsaturated; 0/Linoleic Acids; 2197-37-7/Linoleic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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