| Dietary fat and lung cancer: a case-control study in Uruguay. | |
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MedLine Citation:
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PMID: 9427434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To examine whether dietary fat and cholesterol modifies lung cancer risk, a case-control study was conducted in Uruguay of 426 men diagnosed from 1993 to 1996 with lung cancer, and 419 hospitalized frequency-matched controls. Dietary patterns were assessed using a 64-item food frequency questionnaire, which allowed the calculation of total energy intake. After adjustment for potential confounders through a model which included tobacco smoking, total energy, a term for all vegetables and fruits, and alpha-carotene intake, an increase in risk for total fat intake for all cell types of lung cancer was observed. Adenocarcinoma of the lung was associated strongly with saturated fat intake (odds ratio [OR] = 2.3, 95 percent confidence interval [CI] = 1.2-4.4), whereas small-cell lung cancer was associated with dietary cholesterol (OR = 2.8, CI = 1.1-7.5). These results suggest that the association of saturated fat and cholesterol could be type-specific, but the high correlation existing between dietary lipids precludes any strong statement about this point. |
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Authors:
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E De Stefani; H Deneo-Pellegrini; M Mendilaharsu; J C Carzoglio; A Ronco |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cancer causes & control : CCC Volume: 8 ISSN: 0957-5243 ISO Abbreviation: Cancer Causes Control Publication Date: 1997 Nov |
Date Detail:
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Created Date: 1998-02-10 Completed Date: 1998-02-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9100846 Medline TA: Cancer Causes Control Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 913-21 Citation Subset: IM |
Affiliation:
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Registro Nacional de Cancer, Montevideo, Uruguay. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Aged Aged, 80 and over Case-Control Studies Confidence Intervals Diet / adverse effects Dietary Fats / adverse effects* Humans Incidence Lung Neoplasms / epidemiology* Male Middle Aged Odds Ratio Risk Factors Uruguay / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats |
| Comments/Corrections | |
Comment In:
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Cancer Causes Control. 1997 Nov;8(6):819-20
[PMID:
9427423
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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