Document Detail

Dietary fat-induced postprandial lipemia: effect on arterial oxygen saturation and plasma lactate, triglyceride, and cholesterol levels in subjects with angina pectoris.
MedLine Citation:
PMID:  7386409     Owner:  NLM     Status:  MEDLINE    
The effects of dietary fat-induced lipemia on arterial oxygen tension and plasma lactate, cholesterol, and triglyceride levels were examined in 11 male subjects (average age 60) with a diagnosis of arteriosclerotic coronary vascular disease and angina pectoris. All subjects were alternately fed three isocaloric formula meals consisting of 100 g of cream fat, 100 g of saffola oil, and an isocaloric nonfat cornstarch control meal. Resting values of arterial blood gases and plasma lactate, triglyceride, and cholesterol were measured before (fasting) and at 3 and 5 hr postprandially. Both types of dietary fat produced significant postprandial decreases in plasma lactate, significant increases in plasma triglyceride and cholesterol levels, and no significant changes in arterial oxygen tension. The control meal had no effect upon any value except to transiently increase the plasma lactate. The role of postprandial lipemia in the atherosclerotic process is discussed and a hypothesis for the plasma cholesterol elevation due to dietary fats is presented.
P E Droubay; D L Puppione
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  33     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1980 Jun 
Date Detail:
Created Date:  1980-08-15     Completed Date:  1980-08-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1199-207     Citation Subset:  AIM; IM    
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MeSH Terms
Angina Pectoris / metabolism
Cholesterol / blood
Coronary Disease / metabolism*
Dietary Fats / pharmacology*
Hyperlipidemias / metabolism
Lactates / blood*
Lipids / blood*
Middle Aged
Oxygen / blood*
Triglycerides / blood
Reg. No./Substance:
0/Dietary Fats; 0/Lactates; 0/Lipids; 0/Triglycerides; 57-88-5/Cholesterol; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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