Document Detail

Dietary factors associated with plasma high molecular weight and total adiponectin levels in apparently healthy women.
MedLine Citation:
PMID:  18593824     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Our aim was to investigate associations between dietary factors and high molecular weight (HMW) as well as total adiponectin in a sample of apparently healthy adult Mediterranean women.
DESIGN AND METHODS: Two hundred and twenty women were enrolled in this study. Anthropometric and body composition measurements were performed in all subjects. Fasting blood samples were taken; HMW and total adiponectin concentrations were measured. Food intake was evaluated using 3-day food records. The frequency of consumption of several food groups was approximately quantified in terms of number of servings per day. Furthermore, dietary intakes of betaine, choline, and free choline were estimated.
RESULTS: Women in the highest HMW adiponectin tertile had higher fruit intake compared with those with lower levels, after adjusting for potential confounders (P=0.04). On the contrary, dietary betaine and choline intakes were not different among HMW adiponectin tertiles. In linear models, fruit consumption, controlling for biological and lifestyle variables, was significantly related to HMW adiponectin (partial r=0.15, P=0.04), but the association with total adiponectin did not reach statistical significance (partial r=0.11, P=0.12). A significant negative correlation between total adiponectin and refined cereals was also observed (partial r=-0.16, P=0.03).
DISCUSSION: This is the first study that evaluates associations between dietary factors and HMW adiponectin levels. The associations found are moderate and indicate that, after multivariate adjustment, fruit consumption is related to HMW adiponectin in both linear and nonlinear models.
Mary Yannakoulia; Nikos Yiannakouris; Labros Melistas; Evaggelia Fappa; Nikoletta Vidra; Meropi D Kontogianni; Christos S Mantzoros
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-07-01
Journal Detail:
Title:  European journal of endocrinology / European Federation of Endocrine Societies     Volume:  159     ISSN:  1479-683X     ISO Abbreviation:  Eur. J. Endocrinol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-22     Completed Date:  2008-10-17     Revised Date:  2012-04-09    
Medline Journal Info:
Nlm Unique ID:  9423848     Medline TA:  Eur J Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  R5-10     Citation Subset:  IM    
Department of Nutrition and Dietetics, Harokopio University, Athens 17671, Greece.
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MeSH Terms
Adiponectin / blood,  chemistry
Aged, 80 and over
Betaine / administration & dosage
Blood Glucose
Body Composition
Choline / administration & dosage
Linear Models
Middle Aged
Molecular Weight
Nonlinear Dynamics
Nutrition Assessment*
Reg. No./Substance:
0/ADIPOQ protein, human; 0/Adiponectin; 0/Blood Glucose; 107-43-7/Betaine; 62-49-7/Choline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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