Document Detail


Dietary exposure to dioxins and dioxin-like PCBs in The Netherlands anno 2004.
MedLine Citation:
PMID:  18554765     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, representative occurrence data for PCDD/Fs and dioxin-like PCBs in food were obtained and used to estimate dietary exposure of the Dutch population. Food composite samples were analyzed as well as single fish and vegetables samples. Total dioxin concentrations in animal products ranged from 0.05 pg TEQ/g product in poultry to 2.5 pg TEQ/g product (using TEF(2006)) in fish (shrimp), with 0.12pg TEQ/g product being the lowest concentrations measured in fish (tuna). In vegetable products, concentrations ranged from 0.00002 pg TEQ/g product (white kale) to 0.19 pg TEQ/g (oils and fats). A long-term dietary exposure distribution was calculated using Monte Carlo Risk Assessment software. The lower bound median exposure of the Dutch population to PCDD/Fs and dioxin-like PCBs was estimated at 0.8 pg WHO-TEQ/kgbw/d, half of which were dioxin-like PCBs. Dairy was the main source (38%) due to its high consumption. Time-trend analysis shows that the exposure to dioxins has further decreased by 35% over the past five years. This is due to lower levels of dioxin-like compounds in most of the foods, mainly influenced by lower levels in meat and milk. The use of the new TEFs gives an exposure reduction of 10% with respect to TEF(1998). Still, 4% of the Dutch population exceeds the exposure limit of 14 pg/kgbw/week as set by the EU.
Authors:
Anika De Mul; Martine I Bakker; Marco J Zeilmaker; Wim A Traag; Stefan P J van Leeuwen; Ron L A P Hoogenboom; Polly E Boon; Jacob D van Klaveren
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-04-24
Journal Detail:
Title:  Regulatory toxicology and pharmacology : RTP     Volume:  51     ISSN:  0273-2300     ISO Abbreviation:  Regul. Toxicol. Pharmacol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-30     Completed Date:  2008-09-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214983     Medline TA:  Regul Toxicol Pharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  278-87     Citation Subset:  IM    
Affiliation:
RIKILT-Institute of Food Safety, Wageningen University and Research Centre, P.O. Box 230, Bornsesteeg 45, AE Wageningen, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Carcinogens, Environmental / analysis*
Diet*
Dioxins / analysis*
Environmental Exposure / analysis*,  statistics & numerical data
Environmental Monitoring / methods*,  statistics & numerical data
Food Analysis
Food Contamination / analysis*,  statistics & numerical data
Humans
Netherlands
Chemical
Reg. No./Substance:
0/Carcinogens, Environmental; 0/Dioxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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