Document Detail

Dietary exposure of juvenile common sole (Solea solea L.) to polybrominated diphenyl ethers (PBDEs): Part 1. Bioaccumulation and elimination kinetics of individual congeners and their debrominated metabolites.
MedLine Citation:
PMID:  20888677     Owner:  NLM     Status:  MEDLINE    
The uptake and elimination of six PBDE congeners (BDE-28, -47, -99, -100, -153, -209) were studied in juvenile common sole (Solea solea L.) exposed to spiked contaminated food over a three-month period, then depurated over a five-month period. The results show that all of the studied PBDEs accumulate in fish tissues, including the higher brominated congener BDE-209. Several additional PBDE congeners were identified in the tissues of exposed fish, revealing PBDE transformation, mainly via debromination. The identified congeners originating from PBDE debromination include BDE-49 and BDE-202 and a series of unidentified tetra-, penta-, and hepta- BDEs. Contaminant assimilation efficiencies (AEs) were related to their hydrophobicity (log Kow) and influenced by PBDE biotransformation. Metabolism via debromination appears to be a major degradation route of PBDEs in juvenile sole in comparison to biotransformation into hydroxylated metabolites.
C Munschy; K Héas-Moisan; C Tixier; N Olivier; O Gastineau; N Le Bayon; V Buchet
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental pollution (Barking, Essex : 1987)     Volume:  159     ISSN:  1873-6424     ISO Abbreviation:  Environ. Pollut.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-11-15     Completed Date:  2011-03-01     Revised Date:  2013-08-12    
Medline Journal Info:
Nlm Unique ID:  8804476     Medline TA:  Environ Pollut     Country:  England    
Other Details:
Languages:  eng     Pagination:  229-37     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Biogeochemistry of Organic Contaminants, Rue de l'Ile d'Yeu, BP 21105, 44311 Nantes Cedex 3, France.
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MeSH Terms
Environmental Monitoring
Flatfishes / metabolism*
Halogenated Diphenyl Ethers / metabolism*
Polybrominated Biphenyls / metabolism
Reg. No./Substance:
0/2,2',4,4',5-brominated diphenyl ether; 0/Halogenated Diphenyl Ethers; 0/Polybrominated Biphenyls; 0/hexabrominated diphenyl ether 153; 0/tribromodiphenyl ether 28; 0N97R5X10X/2,2',4,4'-tetrabromodiphenyl ether; 1163-19-5/decabromobiphenyl ether

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