| Dietary egg whites for phosphorus control in maintenance haemodialysis patients: a pilot study. | |
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MedLine Citation:
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PMID: 21288313 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: High dietary protein intake is associated with greater survival in maintenance haemodialysis (MHD) patients. High-protein foods may increase dietary phosphorus burden, which is associated with increased mortality in these patients. Hypothesis is: an egg white based diet with low phosphorus to protein ratio (<1.4 mg/g) will lower serum phosphorus without deteriorating the nutritional status in MHD patients. OBJECTIVE: We assessed serum phosphorus and albumin levels in MHD patients who agreed to ingest one meal per day with pasteurised liquid egg whites without phosphorus additives, as principal protein source. METHODS: Thirteen otherwise stable MHD patients with serum phosphorus >4.0 mg/dl agreed to consume eight ounces (225 g) of pasteurised liquid egg whites one meal per day for six weeks. Recipes were suggested to improve diet variety. RESULTS: Thirteen participating patients included seven women, three African Americans and five diabetics. Twelve patients exhibited drop in serum phosphorus. Mean population fall in serum phosphorus was 0.94 mg/dl, i.e. from 5.58 ± 1.34 (mean ± SD) to 4.63 ± 1.18 (p = 0.003). Serum albumin showed an increase by 0.19 g/dl, i.e. from 4.02 ± 0.29 to 4.21 ± 0.36 g/dl (p = 0.014). Changes in phosphorus pill count were not statistically significant (p = 0.88). The egg white diet was well tolerated, and recipe variety appreciated. CONCLUSION: Pasteurised liquid egg whites may be an effective diet component lowering serum phosphorus without risking malnutrition. Controlled trials are indicated to examine egg white based dietary interventions in MHD patients at home or during haemodialysis treatment. |
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Authors:
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Lynn M Taylor; Kamyar Kalantar-Zadeh; Theodore Markewich; Sara Colman; Debbie Benner; John J Sim; Csaba P Kovesdy |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of renal care Volume: 37 ISSN: 1755-6686 ISO Abbreviation: J Ren Care Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-03 Completed Date: 2011-06-16 Revised Date: 2011-09-22 |
Medline Journal Info:
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Nlm Unique ID: 101392167 Medline TA: J Ren Care Country: France |
Other Details:
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Languages: eng Pagination: 16-24 Citation Subset: N |
Copyright Information:
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© 2011 European Dialysis and Transplant Nurses Association/European Renal Care Association. |
Affiliation:
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DaVita Carroll County Dialysis, Westminster, MD, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Dietary Proteins / administration & dosage* Egg White* Female Humans Kidney Failure, Chronic / blood, diet therapy*, therapy* Male Middle Aged Phosphorus / blood* Pilot Projects Renal Dialysis* Serum Albumin / analysis |
| Grant Support | |
ID/Acronym/Agency:
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K23 DK061162-05/DK/NIDDK NIH HHS; M01-RR00425/RR/NCRR NIH HHS; R21 DK078012-01/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Dietary Proteins; 0/Serum Albumin; 7723-14-0/Phosphorus |
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