Document Detail

Dietary egg whites for phosphorus control in maintenance haemodialysis patients: a pilot study.
MedLine Citation:
PMID:  21288313     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: High dietary protein intake is associated with greater survival in maintenance haemodialysis (MHD) patients. High-protein foods may increase dietary phosphorus burden, which is associated with increased mortality in these patients. Hypothesis is: an egg white based diet with low phosphorus to protein ratio (<1.4 mg/g) will lower serum phosphorus without deteriorating the nutritional status in MHD patients.
OBJECTIVE: We assessed serum phosphorus and albumin levels in MHD patients who agreed to ingest one meal per day with pasteurised liquid egg whites without phosphorus additives, as principal protein source.
METHODS: Thirteen otherwise stable MHD patients with serum phosphorus >4.0 mg/dl agreed to consume eight ounces (225 g) of pasteurised liquid egg whites one meal per day for six weeks. Recipes were suggested to improve diet variety.
RESULTS: Thirteen participating patients included seven women, three African Americans and five diabetics. Twelve patients exhibited drop in serum phosphorus. Mean population fall in serum phosphorus was 0.94 mg/dl, i.e. from 5.58 ± 1.34 (mean ± SD) to 4.63 ± 1.18 (p = 0.003). Serum albumin showed an increase by 0.19 g/dl, i.e. from 4.02 ± 0.29 to 4.21 ± 0.36 g/dl (p = 0.014). Changes in phosphorus pill count were not statistically significant (p = 0.88). The egg white diet was well tolerated, and recipe variety appreciated.
CONCLUSION: Pasteurised liquid egg whites may be an effective diet component lowering serum phosphorus without risking malnutrition. Controlled trials are indicated to examine egg white based dietary interventions in MHD patients at home or during haemodialysis treatment.
Lynn M Taylor; Kamyar Kalantar-Zadeh; Theodore Markewich; Sara Colman; Debbie Benner; John J Sim; Csaba P Kovesdy
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of renal care     Volume:  37     ISSN:  1755-6686     ISO Abbreviation:  J Ren Care     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-03     Completed Date:  2011-06-16     Revised Date:  2014-09-14    
Medline Journal Info:
Nlm Unique ID:  101392167     Medline TA:  J Ren Care     Country:  France    
Other Details:
Languages:  eng     Pagination:  16-24     Citation Subset:  N    
Copyright Information:
© 2011 European Dialysis and Transplant Nurses Association/European Renal Care Association.
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MeSH Terms
Aged, 80 and over
Dietary Proteins / administration & dosage*
Egg White*
Kidney Failure, Chronic / blood,  diet therapy*,  therapy*
Middle Aged
Phosphorus / blood*
Pilot Projects
Renal Dialysis*
Serum Albumin / analysis
Grant Support
K23 DK061162/DK/NIDDK NIH HHS; K23 DK061162-05/DK/NIDDK NIH HHS; M01-RR00425/RR/NCRR NIH HHS; R21 DK078012/DK/NIDDK NIH HHS; R21 DK078012-01/DK/NIDDK NIH HHS; R21 DK078012-02/DK/NIDDK NIH HHS
Reg. No./Substance:
0/Dietary Proteins; 0/Serum Albumin; 27YLU75U4W/Phosphorus

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