Document Detail

Dietary copper intake in artificially fed infants.
MedLine Citation:
PMID:  3789787     Owner:  NLM     Status:  MEDLINE    
Plasma concentrations of copper and zinc and leucocyte concentrations of zinc were measured in mothers during later pregnancy, at delivery, and 8-10 weeks after birth, and plasma concentrations of copper and zinc were measured in their infants at delivery and 8-10 weeks after birth. The 145 infants were either breast fed or fed one of two milk formulas supplying copper at different concentrations. None of the infants achieved the minimum copper intakes recommended by the World Health Organisation (WHO). At 2 months of age there were no major differences in growth or health detected in infants fed the different copper intakes. Infant birth weight correlated well with the ratio of maternal venous plasma zinc:maternal leucocyte zinc at delivery. Maternal venous plasma copper and zinc concentrations at birth correlated with umbilical venous plasma copper and zinc concentrations. Infants fed the higher copper content formulas had a low mean plasma zinc concentration without a significant increase in the mean plasma copper concentration. The present WHO recommendations regarding minimum copper intakes for infants fed formulas cannot be achieved with currently available formulas and are probably wrong.
S Salim; J Farquharson; G C Arneil; F Cockburn; G I Forbes; R W Logan; J C Sherlock; T S Wilson
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  61     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1987-01-20     Completed Date:  1987-01-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1068-75     Citation Subset:  AIM; IM    
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MeSH Terms
Breast Feeding
Copper / administration & dosage*,  blood
Fetal Blood / analysis
Infant Food*
Infant, Low Birth Weight / blood
Infant, Newborn / blood*,  growth & development
Leukocytes / analysis
Zinc / blood
Reg. No./Substance:
7440-50-8/Copper; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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