Document Detail

Dietary cholesterol and coronary heart disease.
MedLine Citation:
PMID:  12361489     Owner:  NLM     Status:  MEDLINE    
Dietary cholesterol has been known as a dominant factor in the genesis of atherosclerosis since 1908. The evidence for the role of dietary cholesterol is based upon animal experiments, the chemistry of atherosclerotic plaques, worldwide epidemiology, and human feeding studies. All lines of evidence converge to indicate that dietary cholesterol is a major factor in promoting the growth of the atherosclerotic plaque by increasing its cholesterol content. Confusion about dietary cholesterol has arisen because amounts above a certain quantity (the ceiling) do not elevate plasma cholesterol and low-density lipoprotein cholesterol. The therapeutic threshold for dietary cholesterol is below 100 mg/d.
William E Connor; Sonja L Connor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  4     ISSN:  1523-3804     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-10-03     Completed Date:  2003-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  425-32     Citation Subset:  IM    
Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, L465, Portland, OR 97239-3098, USA.
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MeSH Terms
Cholesterol, Dietary / administration & dosage*,  adverse effects
Coronary Artery Disease
Coronary Disease / pathology,  prevention & control*
Pregnancy / blood
Reg. No./Substance:
0/Cholesterol, Dietary

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