| Dietary ascorbic acid and muscle carnitine (beta-OH-gamma-(trimethylamino) butyric acid) in guinea-pigs. | |
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MedLine Citation:
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PMID: 7378344 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tissue ascorbic acid (AA) contents of approximately 12 and 100% saturation respectively were produced in two groups of guinea-pigs. The 'low-AA' group had a significantly lower muscle carnitine concentrations than the 'high-AA' group. There was no concomitant emergence of the symptoms customarily regarded as characteristic of hypovitaminosis C. It is concluded that muscle carnitine (beta-OH-gamma-(trimethyl-amino)butyric acid) is a highly-sensitive indicator of tissue AA contents; this could account for the lassitude and fatique reported to precede the emergence of frank scurvy in man. |
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Authors:
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R E Hughes; R J Hurley; E Jones |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of nutrition Volume: 43 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 1980 Mar |
Date Detail:
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Created Date: 1980-08-28 Completed Date: 1980-08-28 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 385-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Ascorbic Acid / analysis Ascorbic Acid Deficiency / metabolism* Carnitine / analysis* Diet Guinea Pigs Male Muscles / analysis* |
| Chemical | |
Reg. No./Substance:
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50-81-7/Ascorbic Acid; 541-15-1/Carnitine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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