Document Detail

Dietary accumulation efficiencies and biotransformation of polybrominated diphenyl ethers in farmed Atlantic salmon (Salmo salar).
MedLine Citation:
PMID:  16192069     Owner:  NLM     Status:  MEDLINE    
The consumer safety of farm-raised salmon could be improved by determining the transfer efficiency of hazardous pollutants from fish feed to the salmon. A controlled feeding trial for 30 weeks was carried out to investigate the transfer of polybrominated diphenyl ethers (PBDEs) in Atlantic salmon (Salmo salar). Using three feed concentrations, an average of 95% of the total PBDE content of feed accumulated in whole salmon. Skinned fillet accumulated 42-59% of the PBDE intake. Equal partitioning according to the lipid content of the tissue was demonstrated. The formation of less brominated PBDEs via preferential debromination from the meta-position was thought to explain the exceptional accumulation efficiencies of BDE 47, BDE 66, BDE 75, BDE 119 and BDE 183 that were either >100% or else increasing with the exposure dose. Monitoring of a larger number of PBDE congeners is recommended to verify the biotransformation routes. The PBDE concentration in salmon of different ages, fed on a known concentration of PBDEs in fish feed, could be predicted by using the accumulation efficiencies determined in this study.
P Isosaari; A-K Lundebye; G Ritchie; O Lie; H Kiviranta; T Vartiainen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Food additives and contaminants     Volume:  22     ISSN:  0265-203X     ISO Abbreviation:  Food Addit Contam     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-29     Completed Date:  2006-01-31     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8500474     Medline TA:  Food Addit Contam     Country:  England    
Other Details:
Languages:  eng     Pagination:  829-37     Citation Subset:  IM    
Department of Environmental Health, National Public Health Institute, PO Box 95, FI-70701 Kuopio, Finland.
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MeSH Terms
Animal Feed / analysis
Flame Retardants / pharmacokinetics
Food Contamination / analysis
Halogenated Diphenyl Ethers
Phenyl Ethers / analysis,  pharmacokinetics*
Polybrominated Biphenyls / analysis,  pharmacokinetics*
Salmo salar / metabolism*
Seafood / analysis
Tissue Distribution
Reg. No./Substance:
0/Flame Retardants; 0/Halogenated Diphenyl Ethers; 0/Phenyl Ethers; 0/Polybrominated Biphenyls; 32534-81-9/pentabromodiphenyl ether

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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