| Dietary Selenium Affects Selenoprotein W Gene Expression in the Liver of Chicken. | |
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MedLine Citation:
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PMID: 21331563 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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As selenium in the form of "Selenoprotein W (SelW)" is essential for the maintenance of normal liver function, the expression of SelW liver depends on the level of selenium supplied with the diet. Whereas this is well known to be the case in mammals, relatively little is known about the effect of dietary Se on the expression SelW in the livers of avian species. To investigate the effects of dietary Se levels on the SelW mRNA expression in the liver of bird, 1-day-old male chickens were fed either a commercial diet or a Se-supplemented diet containing 1.0, 2.0, 3.0, and 5.0 mg/kg sodium selenite (Na(2)SeO(3)) for 90 days. The livers were collected and examined for Se content and mRNA levels of SelW, Selenophosphate synthetase-1, and selenocysteine-synthase (SecS). The data indicate that, within a certain range, a Se-supplemented diet can increase the expression of SelW and the mRNA levels of SecS, and also, that the transcription of SelW is very sensitive to dietary Se. |
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Authors:
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Bo Sun; Rihua Wang; Jinlong Li; Zhihui Jiang; Shiwen Xu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-18 |
Journal Detail:
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Title: Biological trace element research Volume: - ISSN: 1559-0720 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7911509 Medline TA: Biol Trace Elem Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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