| Dietary Protein and Sugar Differentially Affect Development and Metabolic Pools in Ecologically Diverse Drosophila. | |
| | |
MedLine Citation:
|
PMID: 21525254 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
We examined the effects of 3 diets differing in their relative levels of sugar and protein on development and metabolic pools (protein, TG, and glycogen) among sets of isofemale lines of 2 ecologically distinct Drosophila species, D. melanogaster and D. mojavensis. Our high protein:sugar ratio diet contained 7.1% protein and 17.9% carbohydrate, the EPS diet was 4.3% protein and 21.2% carbohydrate, and the LPS was only 2.5% protein and 24.6% carbohydrate. Larvae of D. melanogaster, a generalist fruit breeder, were able to survive on all 3 diets, although all 3 metabolic pools responded with significant diet and diet × line interactions. Development was delayed by the diet with the most sugar relative to protein. The other species, D. mojavensis, a cactus breeder ecologically unaccustomed to encountering simple sugars, completely failed to survive when fed the diet with the highest sugar and showed very poor survival even with the diet with equal parts of protein and sugar. Furthermore, the D. mojavensis adult metabolic pools of protein, TG, and glycogen significantly differed from those of D. melanogaster adults fed the identical diet. Thus, considerable within- and between-species differences exist in how diets are metabolized. Given that the genomes of both of these Drosophila species have been sequenced, these differences and their genetic underpinnings hold promise for understanding human responses to nutrition and for developing strategies for dealing with metabolic disease. |
| | |
Authors:
|
Luciano M Matzkin; Sarah Johnson; Christopher Paight; Goran Bozinovic; Therese A Markow |
Related Documents
:
|
19060384 - Differing effect of protein isolates from different cultivars of blue lupin on plasma l... 19723664 - Scavenger receptor bi facilitates hepatic very low density lipoprotein production in mice. 2614254 - Plasma lipoproteins and apolipoproteins in the preruminant calf, bos spp: density distr... 3989374 - Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density ... 12068254 - Maternal dietary ethanol consumption is associated with hypertriglyceridemia in adult r... 18218774 - Seasonal diet affects ammonia emissions from tie-stall dairy barns. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-4-27 |
Journal Detail:
|
Title: The Journal of nutrition Volume: - ISSN: 1541-6100 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-4-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0404243 Medline TA: J Nutr Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Section of Ecology, Behavior and Evolution and University of California at San Diego, La Jolla, CA 92093. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Consumption of High-Oleic Acid Ground Beef Increases HDL-Cholesterol Concentration but Both High- an...
Next Document: Essential Amino Acids Regulate Both Initiation and Elongation of mRNA Translation Independent of Ins...