Document Detail


Dietary phosphate assessment in dialysis patients.
MedLine Citation:
PMID:  20850345     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Malnutrition is known to be highly prevalent in patients with kidney disease. It is associated with poor clinical prognosis and can result from restricted dietary protein-energy intake. The issue is also compounded by protein wasting that occurs in dialysis patients. In countering malnutrition, an adequate protein intake is essential but limited by its phosphate content. Therefore, an accurate assessment of nutritional status and intake is an important part of the therapeutic strategy for patients on dialysis. Assessing dietary phosphate intake is not straight forward, with many confounding factors requiring consideration. Interview and diet diaries are the preferred means by which dietary intake can be estimated. However, it is evident that these estimates can vary considerably and are subject to underreporting. Moreover, the use of phosphates as additives and their omission from available nutrient databases are significant contributors to this variation and underestimation. This review highlights the main limitations in assessing dietary phosphate intake and introduces the concept of monitoring changes in dietary habit (appetite) as a proxy for dietary protein and energy intake. This review discusses the use of monitoring dietary habit in trials, with phosphate binders as a simple tool to address the possibility that changes to dietary habits may influence phosphate binder efficacy.
Authors:
Alastair M Mathewson; Denis Fouque; Alex J Toft
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-09-20
Journal Detail:
Title:  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation     Volume:  20     ISSN:  1532-8503     ISO Abbreviation:  J Ren Nutr     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-19     Completed Date:  2011-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112938     Medline TA:  J Ren Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Affiliation:
INEOS Healthcare Ltd, Warrington, United Kingdom. alastair.mathewson@ineoshealthcare.com
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MeSH Terms
Descriptor/Qualifier:
Appetite
Diet Records
Dietary Proteins / metabolism
Energy Intake
Europe
Food Habits*
Humans
Interviews as Topic
Kidney Diseases / physiopathology*
Malnutrition / metabolism*
Nutritional Status
Phosphates / metabolism*
Prealbumin / analysis
Renal Dialysis
Serum Albumin / analysis
Chemical
Reg. No./Substance:
0/Dietary Proteins; 0/Phosphates; 0/Prealbumin; 0/Serum Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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