| Dietary L-homoserine spares threonine in chicks. | |
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MedLine Citation:
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PMID: 19474159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Four chick bioassays were conducted to evaluate the threonine (Thr) replacement value of l-homoserine (HS). Growth rate was increased (P < 0.05) by dietary addition of 800 mg l-HS/kg diet to a purified diet severely deficient in Thr or by the addition of 800 or 1000 mg of l-HS/kg diet to a corn-peanut meal diet distinctly deficient in Thr. The addition of an isomolar level of alpha-ketobutyrate, a catabolic product of both Thr and HS, did not elicit a response. Standard-curve methodology predicted a Thr replacement value of 38 +/- 9% for HS. Interactions (P < 0.01) were observed in assays 2 and 4 between dietary Thr adequacy and 800 or 1000 mg l-HS/kg supplementation. Thus, HS improved growth performance when added to a Thr-deficient diet (0.46 g Thr/100 g diet), but it decreased growth performance when added to the same diet containing surfeit Thr (0.80 g Thr/100 g diet). The results indicate that low levels of HS elicit a growth response in young chicks fed Thr-deficient diets. |
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Authors:
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Kasey I Bryant; Ryan N Dilger; Carl M Parsons; David H Baker |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-05-27 |
Journal Detail:
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Title: The Journal of nutrition Volume: 139 ISSN: 1541-6100 ISO Abbreviation: J. Nutr. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-22 Completed Date: 2009-07-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 1298-302 Citation Subset: IM |
Affiliation:
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Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL 61802, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Feed* Animals Arachis hypogaea Chickens / growth & development, metabolism* Diet Homoserine / metabolism*, pharmacology* Threonine / deficiency*, metabolism* Weight Gain Zea mays |
| Chemical | |
Reg. No./Substance:
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498-19-1/Homoserine; 72-19-5/Threonine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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