| Dietary Aloe vera components' effects on cholesterol lowering and estrogenic responses in juvenile goldfish, Carassius auratus. | |
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MedLine Citation:
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PMID: 23135154 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aloes are now considered a very interesting source of bioactive compounds among which phytosterols should play a major role. The present study is an attempt to investigate the hypocholesterolemic activity of Aloe vera associated with its impact on the reproductive status of juvenile goldfish. Therefore, the short- and long-term effects of feeding supplementary diet containing aloe components (20 mg aloe/g diet; 2 %) on plasma lipids, plasma vitellogenin, and hepatic estrogen receptor α/β1 mRNA levels in goldfish were examined. Results of GC-MS for phytosterols show high abundance of β-sitosterol in freeze-dried powder of Aloe vera whole leaves. Moreover, a 2 % aloe powder dietary supplement was not found estrogenic in juvenile goldfish after either 7- or 30-day treatment, but was consistent in plasma hypocholesterolemic effects following long-term exposure. The present data further support that plasma cholesterol modulation induced by phytosterols may not be related to estrogen-like activity. |
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Authors:
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Francesco A Palermo; Paolo Cocci; Mauro Angeletti; Alberto Felici; Alberta Maria Polzonetti-Magni; Gilberto Mosconi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-8 |
Journal Detail:
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Title: Fish physiology and biochemistry Volume: - ISSN: 1573-5168 ISO Abbreviation: Fish Physiol. Biochem. Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100955049 Medline TA: Fish Physiol Biochem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Centro Universitario di Ricerca per lo Sviluppo e la Gestione delle Risorse dell'Ambiente Marino e Costiero (UNICRAM), Università degli Studi di Camerino, Lungomare A. Scipioni 6, 63074, San Benedetto del Tronto, AP, Italy, francesco.palermo@unicam.it. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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