Document Detail

Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohort.
MedLine Citation:
PMID:  15958357     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the association between childhood diet and cardiovascular mortality.
DESIGN: Historical cohort study.
SETTING: 16 centres in England and Scotland.
PARTICIPANTS: 4028 people (from 1234 families) who took part in Boyd Orr's survey of family diet and health in Britain between 1937 and 1939 followed up through the National Health Service central register. EXPOSURES STUDIED: Childhood intake of fruit, vegetables, fish, oily fish, total fat, saturated fat, carotene, vitamin C, and vitamin E estimated from household dietary intake.
MAIN OUTCOME MEASURES: Deaths from all causes and deaths attributed to coronary heart disease and stroke.
RESULTS: Higher childhood intake of vegetables was associated with lower risk of stroke. After controlling for age, sex, energy intake, and a range of socioeconomic and other confounders the rate ratio between the highest and lowest quartiles of intake was 0.40 (95% confidence interval 0.19 to 0.83, p for trend 0.01). Higher intake of fish was associated with higher risk of stroke. The fully adjusted rate ratio between the highest and lowest quartile of fish intake was 2.01 (95% confidence interval 1.09 to 3.69, p for trend 0.01). Intake of any of the foods and constituents considered was not associated with coronary mortality.
CONCLUSIONS: Aspects of childhood diet, but not antioxidant intake, may affect adult cardiovascular risk.
A R Ness; M Maynard; S Frankel; G Davey Smith; C Frobisher; S D Leary; P M Emmett; D Gunnell
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  91     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-06-16     Completed Date:  2005-08-17     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  894-8     Citation Subset:  AIM; IM    
Unit of Paediatric and Perinatal Epidemiology, University of Bristol, Bristol, UK.
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MeSH Terms
Age Distribution
Antioxidants / administration & dosage
Cardiovascular Diseases / etiology*,  mortality
Cause of Death
Child, Preschool
Cohort Studies
Diet / adverse effects*
Great Britain / epidemiology
Middle Aged
Risk Factors
Sex Distribution
Socioeconomic Factors
Stroke / etiology,  mortality
Reg. No./Substance:

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