Document Detail

Diet during pregnancy and total antioxidant capacity in maternal and umbilical cord blood.
MedLine Citation:
PMID:  12422911     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the longitudinal trend of total antioxidant capacity (ToAC) in a group of pregnant women and the relationship with their food habits and ToAC of their newborns. METHODS: ToAC of 12 pregnant women and of umbilical cord blood was determined by means of the oxygen radical absorbance capacity method; mothers' diet was assessed by the dietary history method. RESULTS: Mothers' oxygen radical absorbance capacity values decreased slightly from the first (5.41 +/- 0.28 mmol/l trolox eq.) to the third (5.23 +/- 0.26 mmol/l trolox eq.) trimester of pregnancy, but significantly at delivery (5.06 +/- 0.17 mmol/l trolox eq., p < 0.05 vs. the first, second and third trimesters). Oxygen radical absorbance capacity values of umbilical cord blood (4.87 +/- 0.24 mmol/l trolox eq.) correlated with mothers' values in the third trimester (r = 0.86; p = 0.004) of pregnancy and at delivery (r = 0.87; p = 0.0002). The mothers' diet was rather poor in fruit and vegetables and did not change throughout pregnancy. CONCLUSIONS: The lowering values of ToAC observed during pregnancy may be a physiological trend or a transient imbalance between higher antioxidant requirements and intake which reflects on newborns' ToAC. Nevertheless, efforts should be made to improve dietary habits in pregnancy in order to optimize the ToAC of mothers and newborns.
A Alberti-Fidanza; G C Di Renzo; G Burini; G Antonelli; G Perriello
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  12     ISSN:  1476-7058     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-11-08     Completed Date:  2003-01-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  IM    
Nutrition Section of Department of Internal Medicine, University of Perugia, Italy.
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MeSH Terms
Antioxidants / metabolism*
Fetal Blood / metabolism*
Longitudinal Studies
Pregnancy / blood*
Pregnancy Trimesters / blood
Reg. No./Substance:

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