| Diet and chronic diseases: INCAP studies of atherosclerosis and coronary heart disease. | |
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MedLine Citation:
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PMID: 20461911 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper describes early INCAP studies showing that cholesterol and lipoprotein levels were much lower in the low-income populations of Central America than values that were just beginning to emerge from industrialized countries. These led to the collection of aortas and coronary vessels from 14,610 males and 7,906 females from serial autopsies from 12 public general hospitals in developing countries, mostly in Latin America and in New Orleans and Oslo. The severity of atherosclerotic lesions in the samples was evaluated independently by four pathologists after the samples were randomized, who determined that the severity of atherosclerosis progressed so slowly in the developing country samples that it rarely became clinically significant. The strongest correlation with the severity of lesions was the fat content of the diet. |
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Authors:
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Miguel A Guzm?n |
Publication Detail:
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Type: Comparative Study; Historical Article; Journal Article |
Journal Detail:
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Title: Food and nutrition bulletin Volume: 31 ISSN: 0379-5721 ISO Abbreviation: Food Nutr Bull Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-05-13 Completed Date: 2010-06-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7906418 Medline TA: Food Nutr Bull Country: Japan |
Other Details:
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Languages: eng Pagination: 141-51 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Academies and Institutes
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history* Atherosclerosis / epidemiology, history*, prevention & control Central America / epidemiology Chronic Disease / epidemiology, prevention & control Coronary Disease / epidemiology, history*, prevention & control Diet* / trends Dietary Fats Female History, 20th Century Humans Louisiana / epidemiology Male Norway / epidemiology Risk Factors Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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