Document Detail


Diet and risk of atrial fibrillation – epidemiologic and clinical evidence –.
MedLine Citation:
PMID:  20838006     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dietary factors might affect the risk of atrial fibrillation (AF), but available studies have provided inconsistent results. A review of published observational studies and randomized trials identified 4 dietary exposures that had been investigated regarding AF risk: alcohol, fish-derived n-3 polyunsaturated fatty acids, caffeine, and ascorbic acid. Though studies were highly heterogeneous in their design and results, they showed a consistently increased risk of AF in heavy alcohol drinkers, but no risk associated with moderate alcohol intake. High coffee intake was not clearly associated with an increased risk of AF, and a potential U-shaped association (lower AF risk in moderate drinkers) could exist. High intake of fish-derived n-3 polyunsaturated fatty acids from diet or supplements might prevent AF episodes following cardiovascular events, but no consistent evidence supports an effect in primary prevention. Additional large, well-conducted randomized experiments are necessary to address the role of diet in AF prevention.
Authors:
Noelle N Gronroos; Alvaro Alonso
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2010-09-11
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  74     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-30     Completed Date:  2011-02-23     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  2029-38     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / adverse effects
Animals
Ascorbic Acid / pharmacology
Atrial Fibrillation / etiology*,  prevention & control*
Caffeine / pharmacology
Diet*
Fatty Acids, Omega-3 / pharmacology
Fishes
Humans
Risk
Grant Support
ID/Acronym/Agency:
RC1 HL099452/HL/NHLBI NIH HHS; RC1 HL099452-01/HL/NHLBI NIH HHS; RC1 HL099452-02/HL/NHLBI NIH HHS; RC1HL099452/HL/NHLBI NIH HHS; T32 HL07779/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids, Omega-3; 3G6A5W338E/Caffeine; PQ6CK8PD0R/Ascorbic Acid
Comments/Corrections

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