| Diet and risk of atrial fibrillation – epidemiologic and clinical evidence –. | |
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MedLine Citation:
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PMID: 20838006 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dietary factors might affect the risk of atrial fibrillation (AF), but available studies have provided inconsistent results. A review of published observational studies and randomized trials identified 4 dietary exposures that had been investigated regarding AF risk: alcohol, fish-derived n-3 polyunsaturated fatty acids, caffeine, and ascorbic acid. Though studies were highly heterogeneous in their design and results, they showed a consistently increased risk of AF in heavy alcohol drinkers, but no risk associated with moderate alcohol intake. High coffee intake was not clearly associated with an increased risk of AF, and a potential U-shaped association (lower AF risk in moderate drinkers) could exist. High intake of fish-derived n-3 polyunsaturated fatty acids from diet or supplements might prevent AF episodes following cardiovascular events, but no consistent evidence supports an effect in primary prevention. Additional large, well-conducted randomized experiments are necessary to address the role of diet in AF prevention. |
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Authors:
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Noelle N Gronroos; Alvaro Alonso |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2010-09-11 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 74 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-30 Completed Date: 2011-02-23 Revised Date: 2011-03-10 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 2029-38 Citation Subset: IM |
Affiliation:
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Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alcohol Drinking
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adverse effects Animals Ascorbic Acid / pharmacology Atrial Fibrillation / etiology*, prevention & control* Caffeine / pharmacology Diet* Fatty Acids, Omega-3 / pharmacology Fishes Humans Risk |
| Grant Support | |
ID/Acronym/Agency:
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RC1 HL099452-01/HL/NHLBI NIH HHS; RC1 HL099452-02/HL/NHLBI NIH HHS; RC1HL099452/HL/NHLBI NIH HHS; T32 HL07779/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Omega-3; 50-81-7/Ascorbic Acid; 58-08-2/Caffeine |
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