| Dielectric studies of the paracetamol-lenticular tissue interactions. | |
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MedLine Citation:
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PMID: 21300530 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper reports on the effect of paracetamol on the dielectric behavior of the rabbit lens. Measurements were performed over the frequency range of 100 Hz-100 kHz in air and at the temperature of 35°C. The frequency dependencies of the relative permittivity and dielectric loss for the control and paracetamol-control lenses are described in terms of a power-low, Debye and Cole-Cole relations. The effect of paracetamol on the dielectric properties of the lens is visible in the lower values of the relative permittivity than those for the control sample at the same frequency. In addition, the relaxations around 18 and 46 kHz for the paracetamol-control lens are shifted to lower frequencies compared with the control lens. The results of this work indicate that the present method is useful in detection of the lens toxicity elicited by overdoses of paracetamol in animal. |
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Authors:
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E Marzec; J Olszewski; E Grześkowiak; A Kamińska; A Bienert; K Iwanik |
Publication Detail:
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Type: Journal Article Date: 2011-01-19 |
Journal Detail:
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Title: Colloids and surfaces. B, Biointerfaces Volume: 84 ISSN: 1873-4367 ISO Abbreviation: Colloids Surf B Biointerfaces Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-02-21 Completed Date: 2011-06-01 Revised Date: 2011-09-27 |
Medline Journal Info:
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Nlm Unique ID: 9315133 Medline TA: Colloids Surf B Biointerfaces Country: Netherlands |
Other Details:
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Languages: eng Pagination: 131-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Biophysics, Poznań University of Medical Sciences, Poznań, Poland. ewaklcde@amu.edu.pl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetaminophen
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pharmacokinetics,
pharmacology* Analgesics, Non-Narcotic / pharmacokinetics, pharmacology* Animals Electric Impedance Lens, Crystalline / drug effects* Male Rabbits |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Non-Narcotic; 103-90-2/Acetaminophen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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