Document Detail


Dieldrin pollution of a human food chain.
MedLine Citation:
PMID:  6840795     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1 An incident is described in which excessive mortality amongst a poultry flock alerted veterinarians. Investigation revealed dieldrin in the carcasses and in the wood litter used in the nesting boxes. 2 Because high levels of dieldrin were found also in eggs the Department of Community Medicine was alerted. 3 Those most at risk were the workers who could have absorbed dieldrin by inhalation and percutaneously, and by eating contaminated eggs. A number of other people were at risk having eaten contaminated eggs. 4 Twenty-one workers or members of their families were investigated by case histories and blood levels. They were all clinically well. The highest estimated daily intake of dieldrin in the diet was 3.8 mgm. The highest blood dieldrin level found was 0.016 microgram/ml. This intake was of the same order as the upper limit of no-toxic-effect of long-term daily dosage, but the blood level is well below the level at which symptoms may be expected. The fall in mean blood level over a year is consistent with a long half-life of dieldrin in the human. 5 The conflict of interest in conducting a comprehensive investigation and preventing undue public alarm is discussed, and how this was resolved in this episode is described.
Authors:
D Bell; A F MacLeod
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human toxicology     Volume:  2     ISSN:  0144-5952     ISO Abbreviation:  Hum Toxicol     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-06-10     Completed Date:  1983-06-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8206759     Medline TA:  Hum Toxicol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  75-82     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Dieldrin / analysis,  blood,  toxicity*
Eggs / analysis
Food Contamination*
Humans
Middle Aged
Poultry / metabolism*
Chemical
Reg. No./Substance:
60-57-1/Dieldrin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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