Document Detail


Dicyclomine: cause of abnormally decreased gall bladder ejection with sincalide-stimulated hepatobiliary scintigraphy.
MedLine Citation:
PMID:  22157036     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hepatobiliary scintigraphy with sincalide stimulation is a commonly performed examination to evaluate gall bladder function. The importance of fasting and the possible interference by opioids are well-known considerations in the preparation of patients for this study. We present another medication, dicyclomine, that may interfere with the validity of the results. A 16-year-old girl with abdominal pain underwent hepatobiliary scintigraphy with sincalide stimulation that demonstrated a decreased gall bladder ejection fraction of 3%. Because of concern for the potential anticholinergic effect of dicyclomine therapy, this medication was discontinued, and a repeat examination revealed a normal ejection fraction of 97%.
Authors:
Jesse Woodard; Badreddine Bencherif; Maria Clavell; Judith Joyce
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  37     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  82-5     Citation Subset:  IM    
Affiliation:
From the *Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA; and †Division of Pediatric Gastroenterology, Children's Hospital of Pittsburgh, Pittsburgh, PA.
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