Document Detail


Diatrizoate CT distribution kinetics: a study of human tissue characterization.
MedLine Citation:
PMID:  6833559     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diatrizoate distribution volume (DDV) is a property of living tissue which characterizes the distribution of diatrizoate contrast material within the tissue. This study compiles DDV and enhancement data from computed tomography (CT) of normal human adults. Tissues examined include liver, spleen, muscle, fat, and renal cortex. Four abnormal tissues, a cirrhotic liver, a liver infiltrated with metastatic colon carcinoma, and two examples of renal malignant lymphoma, were used for comparison. Time-DDV and time-enhancement values were generated for the normal tissues after a bolus of intravenous diatrizoate. The CT-DDV appears to be a potentially reliable indicator of diffuse organ pathology.
Authors:
D A Oppenheimer; S W Young
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  7     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  274-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Diatrizoate / diagnostic use,  metabolism*
Humans
Kidney / metabolism,  radiography
Kinetics
Liver / metabolism,  radiography
Spleen / metabolism,  radiography
Tissue Distribution
Tomography, X-Ray Computed*
Grant Support
ID/Acronym/Agency:
1K04 CA00767/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
117-96-4/Diatrizoate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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