| Diastolic response during dobutamine stress echocardiography evaluated by a tissue velocity imaging technique is a sensitive indicator for diagnosing coronary artery disease. | |
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MedLine Citation:
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PMID: 12712012 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Tissue velocity imaging (TVI) is a new method that measures regional myocardial velocities on the basis of color Doppler myocardial imaging principles. METHODS: To diagnose coronary artery disease (CAD) objectively by evaluating left ventricular diastolic responses during dobutamine stress echocardiography (DSE) with TVI, we performed DSE in 22 healthy participants and 28 patients with angina pectoris without wall-motion abnormality at rest. Before and during DSE, we measured the differences of time intervals from the R wave on electrocardiogram to the peak of early diastolic myocardial velocity in the same cardiac cycle between basal segments and midsegments in the septal (dT-S) and inferior (dT-I) walls by TVI. RESULTS: During DSE, dT-S in patients with left anterior descending CAD and dT-I in patients with right CAD were prolonged compared with that in healthy participants (both P <.01). The localization of the segments with a dT-S or dT-I during low-dose (10 microg/kg/min) dobutamine infusion of >32 milliseconds allowed the correct identification of the stenosed vessel in 87% of 23 patients for whom DSE was performed with the TVI technique before coronary angiography. CONCLUSIONS: The analysis of regional left ventricular diastolic responses to dobutamine stress using TVI was useful for the objective diagnosis of CAD. |
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Authors:
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Yasuaki Wada; Kazuya Murata; Kazumi Kimura; Kayo Ueda; Jinyao Liu; Rikimaru Oyama; Nozomu Harada; Nobuaki Tanaka; Akira Takaki; Masunori Matsuzaki |
Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 16 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2003 Apr |
Date Detail:
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Created Date: 2003-04-24 Completed Date: 2003-09-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 309-17 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Medicine, Yamaguchi University School of Medicine, Minami-Kogushi, Ube, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Flow Velocity Blood Pressure / physiology Coronary Disease / physiopathology, ultrasonography* Diastole Echocardiography, Stress* Female Heart Rate / physiology Humans Male Middle Aged Observer Variation Ventricular Dysfunction, Left / physiopathology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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