Document Detail


Diastolic pressure as an index of salt sensitivity.
MedLine Citation:
PMID:  7807501     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper analyses the association between blood pressure and sodium excretion in 3975 individuals aged 20-74 years, selected in a probability sample survey of private households carried out in Rio Grande do Sul, Brazil. Sodium and creatinine titrations were performed in casual urine samples collected at the time of BP measurements. A subsample of 611 subjects provided 24 h urine collections. The regression slopes of systolic pressure on sodium excretion increased when diastolic level was higher. At the lowest levels of diastolic pressure the slope did not differ significantly from zero. The adjusted correlation coefficient then rose progressively to a maximum of +0.41 at diastolic pressures of 95-99 mmHg. Strikingly, at diastolic pressures of > or = 100 mmHg, there was no longer any significant association between systolic pressure and sodium excretion. These results could explain some earlier contradictory findings concerning the role of salt intake in hypertension and provide estimates of expected reduction on the prevalence of hypertension in each diastolic pressure group following a reduction on salt intake of a population.
Authors:
E de A Costa; G Rose; C H Klein; A C Achutti
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of human hypertension     Volume:  8     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-02-02     Completed Date:  1995-02-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  703-9     Citation Subset:  IM    
Affiliation:
National School of Public Health, FIOCruz, Rio de Janeiro, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Diastole*
Humans
Hypertension / etiology*
Middle Aged
Regression Analysis
Sodium / urine*
Sodium Chloride / administration & dosage*
Chemical
Reg. No./Substance:
7440-23-5/Sodium; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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