Document Detail

Diastolic hibernation masquerading as constrictive pericarditis.
MedLine Citation:
PMID:  9591176     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Hibernating myocardium has traditionally been characterized in terms of systolic dysfunction. METHODS: We describe a case in which a 75-year-old patient with significant coronary artery disease was operated upon for classic constrictive pericarditis. RESULTS: At sternotomy, there was no evidence of pericarditis, but marked diastolic without systolic dysfunction remained. After successful coronary revascularization, the patient immediately exhibited dramatic improvement of diastolic performance. Ex vivo evaluation of myocardial contractile function revealed normal myocardial adrenergic responsiveness, indicating a reversible impairment of contractility. CONCLUSION: Diastolic hibernation may therefore represent a unique form of surgically correctable restrictive cardiomyopathy.
B S Cain; D R Meldrum; K S Joo; R J Davis; A H Harken
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  12     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    1997 Jul-Aug
Date Detail:
Created Date:  1998-07-29     Completed Date:  1998-07-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  235-7     Citation Subset:  IM    
Department of Surgery, University of Colorado, Denver 80262, USA.
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MeSH Terms
Cardiomyopathy, Restrictive / diagnosis,  physiopathology,  surgery
Coronary Artery Bypass
Coronary Disease / diagnosis,  physiopathology,  surgery
Diagnostic Errors
Diastole / physiology*
Myocardial Contraction / physiology
Myocardial Stunning / diagnosis*,  physiopathology,  surgery
Pericarditis, Constrictive / diagnosis*,  physiopathology,  surgery
Systole / physiology
Grant Support
Comment In:
J Card Surg. 1997 Jul-Aug;12(4):238-9   [PMID:  9591177 ]

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