Document Detail


Diastolic function study with conventional and pulsed tissue Doppler echocardiography imaging in acromegalic patients.
MedLine Citation:
PMID:  19392840     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acromegaly is associated with myocardial hypertrophy and it can progress to diastolic and systolic dysfunction. PURPOSE: To evaluate diastolic function in acromegalic patients through conventional echocardiography (CD) and tissue Doppler imaging (TDI). METHODS: Seventeen acromegalic patients were submitted to CD and TDI, and early (E) and atriogenic (A) transmitral flow were evaluated in mitral, septal, and tricuspid regions. RESULTS: In comparison with controls the means of conventional (1.06), septal (1.01), and tricuspid (0.98) E/A ratio were significantly lower in acromegalic patients. E/A ratio <1.0 was demonstrated in 41% and 49% of acromegalics by DC and TDI, respectively, with no statistical difference among the two methods. An inverse linear correlation was shown between mitral E/A ratio and acromegalic age (r =-0.7). CONCLUSION: In this study, DC and TDI were equally effective in demonstrating diastolic dysfunction, a common finding in acromegalic patients.
Authors:
Carolina G S Leães; Caroline K Kramer; Julia F S Pereira-Lima; Domingos M Hatem; Iran Castro; Miriam da C Oliveira
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-04-08
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  26     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-14     Completed Date:  2009-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  651-6     Citation Subset:  IM    
Affiliation:
Discipline of Endocrinology, Medicine Faculty, Fundação Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Acromegaly / complications*,  ultrasonography*
Adult
Aged
Elasticity Imaging Techniques / methods*
Female
Humans
Hypertrophy, Left Ventricular / congenital*,  ultrasonography*
Male
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Ultrasonography, Doppler, Pulsed / methods*
Ventricular Dysfunction, Left / congenital*,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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