| Diastolic blood pressure is the first to rise in association with early subclinical obstructive sleep apnea: lessons from periodic examination screening. | |
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MedLine Citation:
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PMID: 12620704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Obstructive sleep apnea syndrome (OSAS) is associated with long-term cardiovascular morbidity. Little is known about these relations at early stages. We conducted a case-control study in which we analyzed the clinical characteristics of young adults who underwent a periodic health examination and were screened for, and eventually found to experience, OSAS. METHODS: We identified 121 subjects newly diagnosed in a sleep study as having OSAS, and 229 matched control subjects in which screening for OSAS was negative. All had a medical interview, physical examination, and routine laboratory tests. RESULTS: Subjects who had OSAS had a higher, body mass index (3-kg/m(2) difference) and a higher diastolic blood pressure (4-mm Hg difference) value, without elevation in systolic blood pressure. There was no metabolic difference (lipids profile and fasting glucose levels) between groups. CONCLUSIONS: Diastolic blood pressure is higher early in the course of OSAS. Long term follow-up may determine effects of prevention and early intervention in OSAS and associated hypertension. |
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Authors:
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Yehonatan Sharabi; Alon Scope; Natasha Chorney; Itamar Grotto; Yaron Dagan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of hypertension Volume: 16 ISSN: 0895-7061 ISO Abbreviation: Am. J. Hypertens. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-03-06 Completed Date: 2003-06-23 Revised Date: 2009-02-24 |
Medline Journal Info:
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Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: United States |
Other Details:
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Languages: eng Pagination: 236-9 Citation Subset: IM |
Affiliation:
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Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA. sharibiy@ninds.nih.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Pressure / physiology* Body Mass Index Female Humans Hypertension / diagnosis, physiopathology*, prevention & control Male Mass Screening Sleep Apnea, Obstructive / diagnosis*, physiopathology*, prevention & control |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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