Document Detail

Diastolic biventricular impairment at long-term follow-up after atrial switch operation for complete transposition of the great arteries: an exercise tissue Doppler echocardiography study.
MedLine Citation:
PMID:  17604961     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to investigate regional myocardial function after atrial switch operation for transposition of the great arteries (TGA) using tissue Doppler echocardiography with strain rate (SR) imaging. METHODS: In all, 24 patients with TGA aged 12 to 33 years and 10 control subjects underwent tissue Doppler echocardiography/SR imaging at rest and during bicycle exercise at 1 and 2 W/kg. Longitudinal function was quantified by strain, SR, and peak velocities measured in the free wall of the systemic ventricle, in septum and in the lateral wall of the subpulmonary ventricle. RESULTS: In patients with TGA, both ventricles showed reduced peak systolic SR values at rest. The increase in peak early diastolic velocity with exercise was reduced in the systemic ventricle (-47 +/- 23 mm/s at rest to -73 +/- 35 mm/s at 2 W/kg, P < .05) and absent in the subpulmonary ventricle (-78 +/- 38 mm/s at rest to -75 +/- 19 mm/s at 2 W/kg) of patients with TGA. CONCLUSION: Exercise tissue Doppler echocardiography/SR imaging identified severely reduced relaxation reserve of both ventricles as typical feature of myocardial dysfunction after atrial repair for TGA.
Tudor C Poerner; Björn Goebel; Hans R Figulla; Herbert E Ulmer; Matthias Gorenflo; Martin Borggrefe; Raoul Arnold
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2007-07-02
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  20     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-06     Completed Date:  2007-12-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1285-93     Citation Subset:  IM    
First Department of Medicine, University Hospital of Jena, Jena, Germany.
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MeSH Terms
Cardiac Surgical Procedures / methods*
Echocardiography, Doppler / methods*
Exercise Test
Follow-Up Studies
Heart Atria / surgery*
Longitudinal Studies
Stroke Volume
Transposition of Great Vessels / surgery*,  ultrasonography*
Treatment Outcome
Ventricular Dysfunction, Left / etiology*,  ultrasonography*

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