Document Detail


Diaphragmatic movement in newborn infants.
MedLine Citation:
PMID:  3280774     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Axial movement of the right hemidiaphragm during tidal breathing was recorded using real-time ultrasonography in 46 healthy term infants. Displacement was 2.6 +/- 0.1, 3.6 +/- 0.2, and 4.5 +/- 0.2 mm (mean +/- SEM) for the anterior, middle, and posterior thirds, respectively. Diaphragmatic movement was significantly greater in the middle and posterior segments than in the anterior segment (P less than 0.0001). Excursion of the diaphragm was similar in sleeping and awake infants, and during quiet and active sleep, as identified by behavioral criteria. Diaphragmatic movement was also assessed in nine infants who required mechanical ventilation and pharmacologic paralysis because of respiratory disease. In these infants, axial movement of the right hemidiaphragm was less in the middle and posterior thirds (P less than 0.05 and P less than 0.01, respectively) than in spontaneously breathing infants, and posterior movement was not predominant. Normative data for axial diaphragmatic movement may be of clinical value in the assessment of defects of the diaphragm, rib cage, or abdomen in newborn infants and may allow further understanding of the direct effects of therapeutic interventions on the respiratory system in infancy.
Authors:
I A Laing; R L Teele; A R Stark
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  112     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-05-06     Completed Date:  1988-05-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  638-43     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, Harvard Medical School, Boston, MA.
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MeSH Terms
Descriptor/Qualifier:
Diaphragm / drug effects,  physiology*,  physiopathology
Humans
Hyaline Membrane Disease / physiopathology*
Infant, Newborn / physiology*
Meconium Aspiration Syndrome / physiopathology*
Pancuronium / pharmacology
Respiration, Artificial
Ultrasonography
Grant Support
ID/Acronym/Agency:
HL34616/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Pancuronium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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