| Diamond-Blackfan anemia associated with Treacher-Collins syndrome. | |
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MedLine Citation:
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PMID: 8217543 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a 2-year-old girl with a rare combination of congenital red cell aplasia or Diamond-Blackfan anemia (DBA) and Treacher-Collins syndrome (TCS). The anemia is only marginally responsive to high-dose corticosteroid, and the child is transfusion dependent. There is no one in the family affected with either DBA or TCS. A hypothesis is advanced that the simultaneous occurrence of the dysmorphism and erythroid agenesis in this case may have been the consequences of an insult to the fetus at the critical stage of development of maxillomandibular structure and the stage of primitive erythroid cell migration from the yolk sac to the fetal liver and bone marrow. |
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Authors:
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R Hasan; S Inoue |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric hematology and oncology Volume: 10 ISSN: 0888-0018 ISO Abbreviation: Pediatr Hematol Oncol Publication Date: 1993 Jul-Sep |
Date Detail:
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Created Date: 1993-12-01 Completed Date: 1993-12-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8700164 Medline TA: Pediatr Hematol Oncol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 261-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Hurley Medical Center, Flint, Michigan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use Blood Transfusion Child, Preschool Combined Modality Therapy Fanconi Anemia / complications*, embryology, therapy Female Humans Infant Mandibulofacial Dysostosis / complications*, embryology |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones |
| Comments/Corrections | |
Comment In:
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Pediatr Hematol Oncol. 1994 Sep-Oct;11(5):561-2, 567-8
[PMID:
7880310
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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