Document Detail

Diamniotic conjoined fetuses in a triplet pregnancy: an insight into embryonic topology.
MedLine Citation:
PMID:  16211442     Owner:  NLM     Status:  MEDLINE    
We present a case of triplets, 2 of whom were monochorionic diamniotic conjoined fetuses, and the other triplet was in a separate chorion. The pregnancy followed in vitro fertilization with 2 embryo transfers and the conjoined fetuses developed from a single embryo. An early ultrasound showed 2 embryos attached to 1 yolk sac. Further monitoring of the pregnancy showed these 2 triplets to be diamniotic with a short umbilical cord/body stalk anomaly. After fetal loss a postmortem examination demonstrated that these fetuses were conjoined with a body stalk anomaly/short umbilical cord syndrome with fusion of the coelomic cavities and small bowel (minimally united/conjoined twins). There were dividing amniotic membranes. This case demonstrates the development of an unusual type of conjoined twin with characteristic features. Conjoined fetuses with this pattern have fused small bowel and cloacal anomalies and often diamniotic placentation, when this is recorded. Various terms including minimally united/conjoined omphalopagus/ischiopagus have been used for this characteristic pattern, but this pattern may warrant a specific term. "Diamniotic vitellopagus" may best reflect the pathogenesis of this pattern.
Adrian Charles; Jan E Dickinson; Susan Watson; Nevile Phillips; John Yovich
Publication Detail:
Type:  Journal Article     Date:  2005-10-05
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  8     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2005 Nov-Dec
Date Detail:
Created Date:  2005-12-21     Completed Date:  2006-01-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  666-72     Citation Subset:  IM    
Department of Pathology, King Edward Memorial Hospital, Bagot Road, Subiaco, WA 6008, Australia.
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MeSH Terms
Abnormalities, Multiple
Amnion / abnormalities*,  pathology
Embryo Transfer
Embryo, Mammalian / abnormalities
Fertilization in Vitro
Fetus / abnormalities*
Twins, Conjoined / embryology*,  pathology*
Ultrasonography, Prenatal

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