Document Detail


Dialysis-induced alterations in left ventricular filling: mechanisms and clinical significance.
MedLine Citation:
PMID:  1996569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative two-dimensional (2-D) and Doppler echocardiography were used to determine whether hemodialysis results in alterations in left ventricular (LV) diastolic filling that might contribute to dialysis-induced hypotension, as well as to assess whether any hemodynamic variables or indices of diastolic filling might be used to identify which patients were at the greatest risk of becoming hemodynamically unstable during dialysis. Sixteen male patients undergoing routine maintenance hemodialysis for end-stage renal disease were prospectively studied before and after hemodialysis. Following hemodialysis there was a significant prolongation (P less than 0.05) in LV isovolumetric relaxation time (IVRT), as well as a significant reduction in the rate and extent of early rapid ventricular filling (P less than 0.005); in contrast, late atrial-assisted filling did not change significantly. A multiple stepwise linear regression analysis of predialysis hemodynamic parameters and noninvasive indices of LV filling showed that there was a significant independent inverse relationship between the frequency of dialysis-related hypotensive episodes and the duration of early LV filling (r = -0.81; P less than 0.001). These results suggest that hemodialysis results in discrete alterations in early LV filling, with no significant compensatory increase in late atrial-assisted ventricular filling. Further, patients with the shortest early LV filling times appeared to have the greatest predilection for becoming hemodynamically unstable during dialysis.
Authors:
J D Rozich; B Smith; J D Thomas; M R Zile; J Kaiser; D L Mann
Related Documents :
12848659 - Ejection fraction: subjective visual echocardiographic estimation versus radionuclide a...
8279369 - Prognostic value of left ventricular mass in uncomplicated acute myocardial infarction ...
17651099 - Myocardial functional and textural findings of the right and left ventricles and their ...
12955429 - Tachycardia exacerbates abnormal left ventricular-arterial coupling in heart failure.
20650609 - The impact of preexisting myocardial remodeling on ventricular function early after tet...
16293529 - Right vs. left ventricular contractile reserve in one-year prognosis of patients with i...
12135139 - Optimal time for predicting left ventricular remodeling after successful primary corona...
22830489 - Myocardium of the superior vena cava, coronary sinus, vein of marshall, and the pulmona...
7272129 - Effect of stenosed and occluded coronary arteries on immediate and late myocardial upta...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  17     ISSN:  0272-6386     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-03-28     Completed Date:  1991-03-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  277-85     Citation Subset:  IM    
Affiliation:
Section of Cardiology, Veterans Administration Medical Center, Charleston, SC.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Computer Simulation
Echocardiography
Echocardiography, Doppler
Electrocardiography
Electrolytes / blood
Humans
Hydrogen-Ion Concentration
Hypotension / physiopathology*
Male
Middle Aged
Renal Dialysis* / adverse effects
Ventricular Function, Left*
Chemical
Reg. No./Substance:
0/Electrolytes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Reactive oxygen species production by monocytes and polymorphonuclear leukocytes during dialysis.
Next Document:  Hemodynamic effects of partial correction of chronic anemia by recombinant human erythropoietin in p...