Document Detail

Dialysis in pregnant women with chronic kidney disease.
MedLine Citation:
PMID:  12969390     Owner:  NLM     Status:  MEDLINE    
Pregnancy occurs uncommonly in women with chronic kidney disease (CKD) and fetal outcome tends to be poor, with high rates of prematurity and mortality. Dialysis, by complementing residual renal function, may improve fetal outcome in pregnant women with CKD. Although there are no prospective or randomized trials that examine the relationship between dialysis and fetal outcome, there is evidence that increased solute clearance, by early initiation of or intensification of dialysis, is beneficial for the health of the fetus. Case reports and observational studies from the United States, Belgium, and Saudi Arabia suggest that there is a relationship between successful pregnancy and the amount of dialysis received. Unfortunately, in these reports, measures of residual renal function and dialysis adequacy are lacking or incomplete. Nonetheless, compared to nonpregnant patients with CKD, in pregnant women with CKD it is reasonable to begin dialysis at a higher level of residual renal function in the hope of improving fetal outcome.
Douglas Shemin
Publication Detail:
Type:  Case Reports; Editorial; Review    
Journal Detail:
Title:  Seminars in dialysis     Volume:  16     ISSN:  0894-0959     ISO Abbreviation:  Semin Dial     Publication Date:    2003 Sep-Oct
Date Detail:
Created Date:  2003-09-12     Completed Date:  2004-02-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8911629     Medline TA:  Semin Dial     Country:  United States    
Other Details:
Languages:  eng     Pagination:  379-83     Citation Subset:  IM    
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MeSH Terms
Kidney Failure, Chronic / therapy*
Pregnancy Complications / therapy*
Renal Dialysis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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