Document Detail

Dialysis dementia in Europe. Report from the Registration Committee of the European Dialysis and Transplant Association.
MedLine Citation:
PMID:  6105349     Owner:  NLM     Status:  MEDLINE    
The diagnosis of dialysis dementia was confirmed in 150 patients treated in sixty-five dialysis centres in Europe in 1976 and 1977. The prevalence was approximately 600 per 100,000 European dialysis patients. The illness was confined to certain geographical areas, 90 of the patients being treated in only fifteen centres. It occurred more frequently in patients dialysed with unprocessed and softened water than in those treated with water processed by deionisation or reverse osmosis. Two-thirds of the patients had osteodystrophy, often painful and fracturing. Morbidity was severe and progressive and only 23 patients were still alive in 1978. The condition seems to be due to aluminium toxicity and should be preventable by water processing in centres where water aluminium content is raised.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1980 Jul 
Date Detail:
Created Date:  1980-10-27     Completed Date:  1980-10-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  190-2     Citation Subset:  AIM; IM    
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MeSH Terms
Aluminum / toxicity*
Apraxias / chemically induced
Myoclonus / chemically induced
Psychoses, Substance-Induced / etiology*
Renal Dialysis / adverse effects*
Renal Osteodystrophy / chemically induced
Speech Disorders / chemically induced
Reg. No./Substance:
0/Solutions; 7429-90-5/Aluminum

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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