| Diagnostics and biomarker development: priming the pipeline. | |
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MedLine Citation:
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PMID: 16718275 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The decrease in the rate at which novel medical products are reaching the market, despite major scientific achievements and investment that might have predicted otherwise, is causing much concern. Although this 'pipeline problem' has often been discussed in the context of drug development, it is also crucial to examine the unique characteristics of the pipeline for biomarkers and diagnostics. Here, we characterize the pipeline problem for biomarkers and diagnostics, and consider what steps could be taken to solve it. |
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Authors:
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Kathryn A Phillips; Stephanie Van Bebber; Amalia M Issa |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review Date: 2006-05-19 |
Journal Detail:
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Title: Nature reviews. Drug discovery Volume: 5 ISSN: 1474-1776 ISO Abbreviation: Nat Rev Drug Discov Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-06-09 Completed Date: 2006-07-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101124171 Medline TA: Nat Rev Drug Discov Country: England |
Other Details:
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Languages: eng Pagination: 463-9 Citation Subset: IM |
Affiliation:
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School of Pharmacy, Institute for Health Policy Studies, and University of California San Francisco, 3333 California Street, Room 420, UCSF BOX 0613, San Francisco, California 94143, USA. phillipsk@pharmacy.ucsf.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers* Congresses as Topic Drug Design* Equipment and Supplies* Humans Interviews as Topic United States United States Food and Drug Administration |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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