| Diagnostic yield of nondiagnostic thyroid nodules is not altered by timing of repeat biopsy. | |
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MedLine Citation:
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PMID: 22667452 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Guidelines from the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference recommend a repeat fine-needle aspiration biopsy (FNAB) after 3 months for thyroid nodules with a nondiagnostic (ND) result. Our aims were to assess which factors influenced their clinical management and to determine if the timing of the repeat FNAB affects the diagnostic yield. Methods: A retrospective institutional review of 298 patients from 1/2006 to 12/2007 with an ND FNAB was performed. The factors influencing the next step in management, including age, gender, history of radiation, presence of Hashimoto's thyroiditis, thyroid-stimulating hormone levels, and ultrasound characteristics, were evaluated. The effect of the time of the repeat FNABs on their diagnostic yield was assessed. Results: Of the 298 patients in our cohort, 9% were referred directly for surgery, 76% had a repeat FNAB, and 15% were observed. Tumor size was the only independent variable correlated with treatment strategy after a ND FNAB. There was not a significant difference in diagnostic yields between repeat FNABs performed earlier than 3 months compared to those preformed later (p=0.58). Conclusion: The timing of repeat FNAB for an initial ND FNAB does not affect diagnostic yield of the repeat FNAB. |
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Authors:
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Carrie C Lubitz; Sushruta S Nagarkatti; William C Faquin; Anthony E Samir; Maria C Hassan; Giuseppe Barbesino; Douglas S Ross; Gregory W Randolph; Randall D Gaz; Antonia E Stephen; Richard A Hodin; Gilbert H Daniels; Sareh Parangi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Thyroid : official journal of the American Thyroid Association Volume: 22 ISSN: 1557-9077 ISO Abbreviation: Thyroid Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-06-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9104317 Medline TA: Thyroid Country: United States |
Other Details:
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Languages: eng Pagination: 590-4 Citation Subset: IM |
Affiliation:
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1 Department of Surgery (Endocrine Surgery Unit), Massachusetts General Hospital , Harvard Medical School, Boston, Massachusetts. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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