Document Detail


Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding.
MedLine Citation:
PMID:  16825907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The endoscopic capsule is a useful tool for visualizing the small bowel in patients with obscure gastrointestinal bleeding. In this study the authors evaluated the diagnostic aid provided by the endoscopic capsule, the factors predicting a significant finding and their impact on the patients' clinical evolution. METHODS: A total of 100 patients (52 men and 48 women, average age 64.4 years) underwent capsule endoscopy. Of this group, 52 patients presented with obscure-overt bleeding and 48 with obscure-occult bleeding. After an average follow-up time of 11.4 months, the clinical outcome was evaluated in 95 patients. RESULTS: The endoscopic capsule identified significant findings in 68% of patients. The most common diagnosis (33.8%) was angiodysplasias. The most important factor predicting significant findings was the previous need for transfusion in the overt bleeding group. As the result of the findings, a specific intervention was made in 75.8% of patients. At the end of follow-up, the clinical outcome was considered positive in 71.6% of patients. Capsule retention occurred in one patient, who required surgery. CONCLUSION: In patients with obscure gastrointestinal bleeding, capsule endoscopy provides a high degree of diagnostic aid. The best candidates for this procedure are patients with obscure-overt bleeding who have required blood transfusions. Capsule endoscopy has a positive influence on an important proportion of patients, whether oriented towards new diagnostic techniques or towards a definitive treatment.
Authors:
Emilio Estévez; Benito González-Conde; José Luis Vázquez-Iglesias; Maria de Los Angeles Vázquez-Millán; Sonia Pértega; Pedro A Alonso; Joan Clofent; Eva Santos; José Luis Ulla; Eloy Sánchez
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  18     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-07     Completed Date:  2007-04-03     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  881-8     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Complexo Hospitalario Juan Canalejo, A Coruña, Spain. estevez@canalejo
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Blood Transfusion
Capsule Endoscopy*
Female
Follow-Up Studies
Gastrointestinal Hemorrhage / diagnosis*,  etiology*,  therapy
Humans
Male
Middle Aged
Predictive Value of Tests
Prospective Studies
ROC Curve
Treatment Outcome
Comments/Corrections
Comment In:
Eur J Gastroenterol Hepatol. 2006 Aug;18(8):873-4   [PMID:  16825904 ]

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