| Diagnostic workup in carotid stenosis-a neurologist's perspective. | |
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MedLine Citation:
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PMID: 20405113 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carotid artery stenosis is associated with the risk of stroke, myocardial infarction, and vascular death. In selected patients, revascularization of carotid narrowing by endarterectomy may reduce the risk of stroke distal to the stenosis. Carotid artery stenting has evolved as a potential alternative to endarterectomy. Four randomized clinical trials comparing safety and efficacy of endarterectomy versus stenting of symptomatic carotid stenosis have been published in recent years, but there remains some uncertainty about the implications of these trials for clinical routine. Both carotid stenting and endarterectomy are based on different treatment strategies which may result in different specific risk factors associated with each procedure. Hence, the procedural risk of either modality varies not only with the skills of the surgeon or the interventionalist but may depend on patient characteristics. It appears that the most important question is not whether one revascularization modality is superior but for which patient one modality is better than the other. A comprehensive diagnostic workup of patients with carotid stenosis based on a broad panel of covariates that affect the risk of vascular events may improve selection of patients for carotid revascularization and may help to decide for whom one revascularization modality is likely to be better than the other. |
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Authors:
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Michael Rosenkranz; Christian Gerloff |
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Publication Detail:
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Type: Journal Article Date: 2010-04-20 |
Journal Detail:
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Title: Neuroradiology Volume: 52 ISSN: 1432-1920 ISO Abbreviation: Neuroradiology Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-25 Completed Date: 2010-10-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: Germany |
Other Details:
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Languages: eng Pagination: 619-28 Citation Subset: IM |
Affiliation:
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Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. rosenkranz@uke.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Carotid Stenosis / diagnosis*, epidemiology, pathology, surgery Comorbidity Humans Neurologic Examination / methods Patient Selection Severity of Illness Index Sex Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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