Document Detail

Diagnostic value of stress echocardiography for the detection of restenosis after PTCA.
MedLine Citation:
PMID:  15686767     Owner:  NLM     Status:  MEDLINE    
Stress echocardiography (SE) has become a widely accepted clinical tool for the non-invasive diagnosis of coronary artery disease (CAD). Previous studies have confirmed that SE has superior diagnostic value compared to exercise ECG testing. SE has also emerged as a cost-effective alternative to nuclear imaging techniques in patients where symptoms and/or conventional ECG stress testing have provided ambiguous results. Several studies have investigated the value of SE to detect significant restenosis after PTCA. However, in these studies, different methods have been used to induce cardiovascular stress such as physical exercise by bicycle or treadmill, pharmacologic stress testing (with dipyridamole or dobutamine) or transoesphageal atrial pacing. This review evaluates the published database of SE to detect restenosis in patients after successful PTCA. It includes 13 studies with a total of 989 patients performed at 3-6 months after the primary intervention. The diagnostic value, utility and limitations of SE is presented and discussed. The data show that SE has a high diagnostic value for detecting significant restenosis after PTCA. Mean sensitivity of SE was 74% (CI 69-79%), mean specificity was 87% (CI 84-89%). The positive predictive value (PPV) of SE was 83%, the overall negative predictive value (NPV) 97%. We conclude that, in the follow-up of patients after PTCA, SE has distinct advantages over other non-invasive methods and is a recommended method for the detection of those to be considered for repeat angiography.
A Scherhag; S Pfleger; K K Haase; T Sueselbeck; M Borggrefe
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of cardiology     Volume:  98     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-02     Completed Date:  2005-05-26     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  191-7     Citation Subset:  IM    
I. Medical Clinical, University Hospital Mannheim, Faculty of Clinical Medicine Mannheim, University of Heidelberg, D-68135 Mannheim, Germany.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Restenosis / ultrasonography*
Coronary Stenosis / therapy*
Dipyridamole / diagnostic use
Echocardiography, Stress*
Sensitivity and Specificity
Vasodilator Agents / diagnostic use
Reg. No./Substance:
0/Vasodilator Agents; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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