Document Detail

Diagnostic value of renography for detection of unilateral renal or renovascular disease in hypertensive patients.
MedLine Citation:
PMID:  1188287     Owner:  NLM     Status:  MEDLINE    
In an effort to find an optimal set of renographic reference parameters for the study of hypertensive patients, the renographic data from 50 hypertensive patients with unilateral renal or renovascular disease were assessed against 95% confidence intervals obtained in normal subjects and in patients with essential hypertension in two different states of hydration. The highest all-over nosographic sensitivity and specificity were obtained by using the data from hydrated normal subjects as reference parameters. The nosographic sensitivity and specificity found in the selected series of hypertensive patients were converted to the clinically relevant predictive values of a positive and a negative test by assuming the prevalence of unilateral renal or renovascular disease in hospital populations of hypertensive patients to be 5% or 10%. In these model populations the predictive value of a postive was 33% and 51%, respectively. The predictive value of a negative test was higher than 99% for both populations. We find that predictive values of that order of magnitude are satisfactory for a test to be used in the initial phase of a diagnostic process.
J Giese; P Mogensen; O Munck
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of clinical and laboratory investigation     Volume:  35     ISSN:  0036-5513     ISO Abbreviation:  Scand. J. Clin. Lab. Invest.     Publication Date:  1975 Jul 
Date Detail:
Created Date:  1976-01-16     Completed Date:  1976-01-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404375     Medline TA:  Scand J Clin Lab Invest     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  307-10     Citation Subset:  IM    
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MeSH Terms
Hypertension, Renal / diagnosis*,  etiology,  radiography
Radioisotope Renography*
Renal Artery / radiography
Renal Artery Obstruction / complications,  diagnosis*,  radiography

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