Document Detail

Diagnostic value of fiberoptic bronchoscopy in lung cancer presenting as mediastinal mass(es).
MedLine Citation:
PMID:  498055     Owner:  NLM     Status:  MEDLINE    
The diagnostic yields of prebonchoscopy sputum specimens and fiberoptic bronchoscopy (including brushings, washings, and/or biopsies) were determined in 35 patients who presented primarily with middle or anterior mediastinal and/or paratracheal mass(es) on chest radiographs. The diagnosis was confirmed on histopathology of tissue obtained by needle biopsy, mediastinoscopy, thoracotomy, and/or autopsy. Thirty-one of the patients were found to have primary bronchogenic carcinomas. At bronchoscopy, extrinsic compression of trachea and/or bronchi was visualized in 23 (Group I) and the tracheobronchial tree appeared normal in 12 (Group II). Prebronchoscopy sputa gave a positive yield in only three of the 35 (8%) patients; the yield was similar in both groups of patients. One or more of the bronchoscopic modalities were diagnostic in 69% of Group I patients but were not helpful in Group II patients. The diagnostic yield of brushings, washings, and biopsies in Group I patients was 52%, 61%, and 37%, respectively. The addition of biopsies to washings and/or brushings did not significantly alter the yield. Washings and brushings are recommended as useful, non-invasive procedures in diagnosing middle mediastinal masses with extrinsic compression. Sputum cytology gives a very low yield.
Z Mohsenifar; S K Chopra; D H Simmons
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  44     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1980-01-24     Completed Date:  1980-01-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1894-6     Citation Subset:  AIM; IM    
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MeSH Terms
Diagnostic Errors
Fiber Optic Technology
Lung Neoplasms / diagnosis*
Mediastinal Neoplasms / diagnosis*
Sputum / cytology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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